Inombolo ye-Cas: 21187-98-4 Isithombe Esifakiwe se-Molecular Formula

Inombolo ye-Cas: 21187-98-4 I-Molecular Formula

Incazelo emfushane:

Inombolo yeCas: 21187-98-4

Igama Lekhemikhali:

I-Molecular Formula:C15H21N3O3S

Synonimes:BP;)-4-methyl-;1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea;1-(hexahydrocyclopenta(c)pyrrol-2(1h )-yl)-3-(p-tolylsulfonyl)-ure;1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl)urea;benzenesulfonamide,n-(((hexahydrocyclopenta() c)pyrrol-2(1h)-yl)amino)carbonyl;n-(4-methylbenzenesulfonyl)-n'-(3-azabicyclo(3.3.0)oct-3-yl)urea;Tetrabenzyl Voglibose HCl

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ukucaciswa Kwemikhiqizo

I-Melting Point	163-169 °C
Ukuminyana	1.2205 (isilinganiso esinzima)
izinga lokushisa lokugcina	Umkhathi ongenayo, Izinga lokushisa Legumbi 2-8°C
ukuncibilika	i-methylene chloride: i-soluble
umsebenzi optical	N/A
Ukubukeka	Okuqinile Okumhlophe
Ubumsulwa	≥98%

Incazelo

iyi-ejenti yomlomo ye-antihyperglycemic esetshenziselwa ukwelapha isifo sikashukela sohlobo II.Kungokwesigaba se-sulfonylurea se-insulin secretagogues, evuselela ama-β-cell we-pancreas ukuthi akhulule i-insulin.ibophezela ku-β cell sulfonyl urea receptor (SUR1), iphinde ivimbele iziteshi ze-potassium ezibucayi ze-ATP.Ngakho-ke, i-potassium efflux yehla kakhulu, okubangela ukuwohloka kwamaseli e-β.Ngemuva kwalokho iziteshi ze-calcium ezincike ku-voltage ku-β cell ziyavuleka, okuholela ekusebenzeni kwe-colodulin, okuholela ekuphumeni kwe-insulin equkethe ama-secretory granules.Ucwaningo lwakamuva luphinde lwabonisa ukuthi lungathuthukisa ngempumelelo isimo se-anti-oxidant kanye ne-nitric oxide-mediated vasodilation ku-Type 2 yesifo sikashukela futhi ivikele amaseli e-pancreatic beta emonakalweni we-hydrogen peroxide.

ukusetshenziswa kanye nomthamo

i-oral hypoglycemic agent esetshenziselwa ukwelapha isifo sikashukela esingancikile ku-insulin.Ukwelashwa kwesifo sikashukela esihambisana nokukhuluphala ngokweqile noma isifo semithambo, kubantu abadala abanesifo sikashukela sohlobo 2. Isifo sikashukela yisimo sempilo esingapheli (esihlala isikhathi eside) esithinta indlela umzimba wakho ophenduka ngayo. ukudla kube amandla.Yehlisa amazinga kashukela egazini ngokuvuselela ukukhiqizwa kwe-insulin kuma-β-cell eziqhingini zeLangerhans.