Inombolo ye-Cas: 168273-06-1 I-Molecular Formula:C22H21Cl3N4O
I-Melting Point | 154.7 °C |
Ukuminyana | 1.299 |
izinga lokushisa lokugcina | akukho mingcele. |
ukuncibilika | I-Soluble ku-DMSO (kufika ku-20 mg/ml) noma ku-Ethanol (kufika ku-20 mg/ml).i-dimethyl sulfoxide futhi ayincibiliki ku-benzene noma i-hexane. |
umsebenzi optical | N/A |
Ukubukeka | i-crystal powde emhlophe kuya kokuphuzi |
Ubumsulwa | ≥98% |
ungumphikisi ophambene we-cannabinoid receptor (CB1).Isebenza ngokuvimbela ngokukhetha ama-receptors e-CB1 atholakala ebuchosheni nasezithweni zangasese ezibalulekile ku-glucose kanye ne-lipid metabolism, okuhlanganisa izicubu ze-adipose, isibindi, i-gastrointestinal tract, kanye nemisipha.Ngakho-ke, kuyindlela yokwelapha yokukhuluphala kanye nezici eziyingozi zenhliziyo.Njengomuthi we-anorectic antiobesity, wawusetshenziswa njengesengezo ekudleni nasekuvivinyeni iziguli ezikhuluphele noma ezikhuluphele ezinezimo eziyingozi ezihambisanayo eYurophu ngo-2006. Noma kunjalo, imiphumela emibi ehlanganisa ukuzibulala, ukucindezeleka, nokukhathazeka kwabikwa, ngokusekelwe lapho i-rimonadant ihoxisiwe. emhlabeni wonke ngo-2008.
Ama-cannabinoids endabuko ahlobene nomthelela ojabulisayo we-nicotine, njenge-cannabinoid receptor blocker, nayo ihlolwa njengendlela yokwelapha engase ibe khona yokulwa nokubhema.
iyi-immunomodulatory CB1 receptor inverse agonist
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