Inombolo ye-Phenformin Cas: 834-28-6 I-Molecular Formula: C10H16N8
I-Melting Point | 150-155 ℃ |
Ukuminyana | 1.197g/cm³ |
izinga lokushisa lokugcina | 2-8℃ |
ukuncibilika | Inokuncibilika okuthile emanzini, incibilika kalula ku-methanol ne-isopropanol, futhi kunzima ukuyincibilika ku-chloroform ne-ether. |
umsebenzi optical | +27.0 degrees (C=1, amanzi). |
Ukubukeka | i-crystalline powder emhlophe |
I-Phenformin isetshenziswa kakhulu ekwelapheni isifo sikashukela sabadala esingancike ku-insulin kanye nesifo sikashukela esincike ku-insulin.Umsebenzi ukukhuthaza ukumukeka kanye ne-glycolysis ye-glucose ngamaseli emisipha, ukunciphisa ukukhiqizwa kwe-glucose ngesibindi, futhi kube nomphumela we-antihyperglycemic.Ingasetshenziswa ngokuhambisana ne-insulin, okwenza kube lula ukulawula ushukela wegazi kanye nokunciphisa umthamo we-insulin.Ngesifo sikashukela esikhuluphele, singasetshenziswa futhi ukuvimbela isifiso sokudla kanye nokumunca i-glucose emathunjini ukuze kwehliswe isisindo.
I-Phenformin isetshenziswa kakhulu ekwelapheni isifo sikashukela sabadala esingancike ku-insulin kanye nesifo sikashukela esincike ku-insulin.Umsebenzi ukukhuthaza ukumukeka kanye ne-glycolysis ye-glucose ngamaseli emisipha, ukunciphisa ukukhiqizwa kwe-glucose ngesibindi, futhi kube nomphumela we-antihyperglycemic.Ingasetshenziswa ngokuhambisana ne-insulin, okwenza kube lula ukulawula ushukela wegazi kanye nokunciphisa umthamo we-insulin.Ngesifo sikashukela esikhuluphele, singasetshenziswa futhi ukuvimbela isifiso sokudla kanye nokumunca i-glucose emathunjini ukuze kwehliswe isisindo.
Ukuphatha ngomlomo: Umthamo osetshenziswa kakhulu ngu-50-200mg ngosuku, othathwe ngemithamo emithathu.Ekuqaleni, thatha 25mg kanye, izikhathi 2-3 ngosuku, ngaphambi kokudla.Ingakhula kancane kancane ibe ngu-50-100mg ngosuku.Ngokuvamile, ushukela wegazi uyancipha ngemva kwesonto elilodwa lomuthi, kodwa ukuze ufinyelele amazinga ajwayelekile kashukela egazini, imithi idinga ukuqhubeka amasonto angu-3-4.