Inombolo ye-Cas: 68077-27-0 I-Molecular Formula: C12H14Cl2FNO4S

Imikhiqizo

Inombolo ye-Cas: 68077-27-0 I-Molecular Formula: C12H14Cl2FNO4S

Incazelo emfushane:

Inombolo yeCas: 68077-27-0

Igama Lekhemikhali:

I-Molecular Formula:C12H14Cl2FNO4S

Synonyms: Noroxin, Fulgram


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ukucaciswa Kwemikhiqizo

I-Melting Point 220 °
Ukuminyana 1.344(isilinganiso esinzima)
izinga lokushisa lokugcina 2-8°C
ukuncibilika I-Soluble ku-DMSO
umsebenzi optical N/A
Ukubukeka Okumhlophe kuya kokumhlophe
Ubumsulwa ≥99%

Incazelo

I-hydrochloride iyimithi elwa namagciwane ene-spectrum ebanzi esebenza ngokumelene nawo womabili amagciwane e-Gram-positive kanye ne-Gram-negative, asebenza ngokuvimbela i-DNA gyrase.Ithagethi: I-DNA gyrase;I-Antibacterial iyi-synthetic chemotherapeutic antibacterial agent esetshenziswa ngezikhathi ezithile ukwelapha izifo ezivamile kanye neziyinkimbinkimbi zomgudu womchamo.iyimithi elwa namagciwane ene-spectrum ebanzi esebenza ngokumelene nawo womabili amagciwane e-Gram-positive kanye ne-Gram-negative.Isebenza ngokuvimbela i-DNA gyrase, uhlobo lwe-II topoisomerase, ne-topoisomerase IV, ama-enzyme adingekayo ukuze ahlukanise i-DNA yebhaktheriya, ngaleyo ndlela avimbele ukuhlukana kwamangqamuzana. Okwamanje kukhona ukusetshenziswa okuthathu okugunyaziwe kubantu abadala (olunye lwazo lukhawulelwe) kanti okunye okungasebenzi ngenxa ukumelana namagciwane.I-Chibroxin (i-ophthalmic) igunyazwe ukuthi isetshenziswe ezinganeni ezineminyaka engaphezu konyaka ubudala. ihlotshaniswa nenani lokusabela okubi okungathí sina okungavamile kanye nokugqabuka kwemisipha okuzenzakalelayo kanye ne-peripheral neuropathy engalungiseki.Izinkinga ze-tendon zingase zibonakale isikhathi eside ngemva kokuba ukwelashwa sekuqediwe futhi ezimweni ezimbi kakhulu kungase kubangele ukukhubazeka impilo yonke.I-Hepatoxicity eholela ekufeni nayo iye yabikwa ngokusetshenziswa kwe-

ukusetshenziswa kanye nomthamo

Ukuze uthole i-solubility ephakeme, sicela ufudumale ithubhu ku-37 ℃ bese uyinyakazisa kubhavu we-ultrasonic okwesikhashana.Isixazululo se-stock singagcinwa ngaphansi -20℃ izinyanga ezimbalwa.
Sincoma ukuthi ulungiselele futhi usebenzise isixazululo ngosuku olufanayo.Kodwa-ke, uma uhlelo lokuhlola ludinga, izixazululo zesitoko zingalungiswa kusenesikhathi, futhi isisombululo sesitoko kufanele sivalwe futhi sigcinwe ngaphansi kuka -20 ℃.Ngokuvamile, isisombululo sesitoko singagcinwa izinyanga ezimbalwa.
Ngaphambi kokusebenzisa, sincoma ukuthi ushiye i-vial ekamelweni lokushisa okungenani ihora ngaphambi kokuyivula.

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