Inombolo ye-Azithromycin Cas: 83905-01-5 I-Molecular Formula: C38H72N2O12

Incazelo emfushane:

Inombolo yeCas: 83905-01-5

Igama leKhemikhali: Azithromycin

I-Molecular Formula:C38H72N2O12

Synonimes:(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R) -13- [(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L- ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-( dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ukucaciswa Kwemikhiqizo

I-Melting Point	115°C
Ukuminyana	1.18 g/cm³
izinga lokushisa lokugcina	Umkhathi ongenayo, Izinga lokushisa Legumbi 2-8°C
ukuncibilika	I-DMF: 16 mg/ml I-DMSO: 5 mg/mlm I-Ethanol: 16 mg/ml I-Ethanol:PBS(pH 7.2) (1:1): 0.50 mg/ml
umsebenzi optical	N/A
Ukubukeka	Impushana Emhlophe
Ubumsulwa	≥98%

Incazelo

UManus Aktteva Biopharma LLP, inkampani yomhlaba wonke ehlinzeka nge-Azithromycin (CAS No.: 83905-01-5) inikeza ngezidingo zakho zenani le-RND / Ukuthuthukiswa noma izimakethe, ngokusekelwe esimweni somkhiqizo.

ISIVIVINYO : Nakuba konke ukukhuthala okufanele okukhona kuzokwenziwa futhi sizobambisana kuzo zonke izindaba uma kuphakama noma iyiphi inkinga ngesikhathi sokuthola usizo , ngeke sithweswe icala nganoma yikuphi ukungathobeli noma izinkinga ezikhona ekwenziweni okungenzeka, okungaphezu kwamandla ethu.Imikhiqizo iyawa. esigabeni sezinto ezilawulwayo/uhlu lwesheduli yemithi izothunyelwa isuka ngqo kumkhiqizi kuphela uma kutholwa imvume yokungenisa yoqobo ekhishwe iziphathimandla ezithintekayo zezwe elingenisayo.• Sicela wazi ukuthi sisebenza ngokuhambisana ngokugcwele nomthetho futhi asephuli noma yikuphi. imithetho esifundeni noma emhlabeni jikelele.Amarekhodi ethu asesidlangalaleni akhuluma ngokwethembeka kwethu.Asikhuthazi noma asifuni ukuba yingxenye yanoma yiziphi izinhlangano ezizimele noma zomphakathi ukufakazela ukuthobela kwethu.

AMAGUNYA Imikhiqizo evikelwe ngamalungelo obunikazi asemthethweni ayinikeziwe ukuze ithengiswe emazweni lapho ukuthengiswa kwemikhiqizo enjalo kuwukwephulwa kwelungelo lobunikazi futhi isibopho sakhona sisengozini yomthengi.Imikhiqizo okwamanje embozwe Amalungelo Obunikazi avumelekile ase-US inikezwa ukusetshenziswa kwe-R&D ngokuhambisana ne-35 USC 271 +A13(1)•U-Manus Aktteva Biopharma LLP akanasibopho/isikweletu uma inikezwa impahla ephula impahla yengqondo nganoma iyiphi indlela ehlanganisa amalungelo obunikazi banoma yimuphi umuntu.U-Manus Aktteva Biopharma LLP akenzi izethulo noma iziqinisekiso zanoma yiluphi uhlobo, okuvezayo noma okushiwo, mayelana nokwangempela noma ukwethembeka maqondana nempahla yengqondo, ehlanganisa amalungelo obunikazi emikhiqizweni noma amasevisi ayo nganoma iyiphi injongo.U-Manus Aktteva Biopharma LLP uxwayisa abathengisi ukuthi bangathengisi noma yiziphi izimpahla ezephula ubunikazi bengqondo nganoma iyiphi indlela ehlanganisa amalungelo obunikazi banoma yimuphi umuntu.U-Manus Aktteva Biopharma LLP uxwayisa abathengi ukuthi bangasebenzisi/bathenge noma yiziphi izimpahla ukuze bathole umkhiqizo okungenzeka ukuthi ngamabomu ubangela ukwephulwa kwempahla yengqondo nganoma iyiphi indlela ehlanganisa amalungelo obunikazi banoma yimuphi umuntu.

ukusetshenziswa kanye nomthamo

I-Azithromycin iyi-semi-synthetic, i-erythromycin enwetshiwe eyindandatho ekhiqizwa ukuhlelwa kabusha kuka-Beckmann kwe-erythromycin oxime kanye nokunciphisa ku-imine ether, kulandelwa i-reductive methylation.I-Azithromycin yayingeyokuqala yama-azalides futhi yayiklanyelwe ukuthuthukisa ukuzinza kanye nengxenye yempilo ye-erythromycin A, kanye nokwenza ngcono umsebenzi wokulwa namagciwane e-Gram negative.Kusukela yatholwa ngo-1980 ngu-Djokic kanye nozakwabo, i-azithromycin ijabulele impumelelo enkulu yokwelapha.