Inombolo ye-Oxytetracycline Cas:2058-46-0 I-Molecular Formula: C22H24N2O9•HCl
I-Melting Point | 180 ° |
Ukuminyana | 1.0200 (isilinganiso esinzima) |
izinga lokushisa lokugcina | Umkhathi ongenayo,Izinga lokushisa Legumbi 0-6°C |
ukuncibilika | > 100 g/L |
umsebenzi optical | N/A |
Ukubukeka | Impushana Ephuzi |
Ubumsulwa | ≥97% |
I-Oxytetracycline iyi-analog ye-tetracycline ehlukanisiwe ne-actinomycete Streptomyces rimosus.I-Oxytetracycline iyimithi elwa namagciwane eboniswa ekwelapheni izifo ezibangelwa amagciwane e-Gram positive kanye ne-Gram negative njenge-Mycoplasma pneumoniae, i-Pasteurella pestis, i-Escherichia coli, i-Haemophilus influenzae, ne-Diplococcus pneumoniae.Isetshenziswa ocwaningweni lwe-oxytetracycline-resistance gene (otrA).I-Oxytetracycline hydrochloride isetshenziselwa ukutadisha ukuhlanganiswa kwe-phagosome-lysosome (PL) kumaseli e-P388D1 kanye nokuba sengozini kwama-antibiotic e-Mycoplasma bovis isolate.
I-Oxytetracycline hydrochloride iwusawoti olungiswe ku-oxytetracycline usebenzisa leli qembu eliyisisekelo le-dimethylamino elikhiqiza ama-protonate ukuze akhe usawoti kuzixazululo ze-hydrochloric acid.I-hydrochloride iwukwakhiwa okuncanyelwayo kwezicelo zemithi.Njengawo wonke ama-tetracycline, i-oxytetracycline ikhombisa umsebenzi obanzi we-antibacterial kanye ne-antiprotozoan futhi isebenza ngokubophezela kumayunithi amancane e-30S kanye ne-50S ye-ribosomal, ivimbe ukuhlanganiswa kwamaprotheni.